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Biology, biography, and the translational gap

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Science Translational Medicine  13 Feb 2019:
Vol. 11, Issue 479, eaat7027
DOI: 10.1126/scitranslmed.aat7027

Figures

  • Fig. 1 Circumnavigating the Valley of Death.

    The image shows the Zabriskie Point in Death Valley National Park, California. Just as gold prospectors saw their hopes for discovery die in the heat of the Death Valley desert, so too do many potential new treatments fail in the translation from discovery to clinical application. There are myriad reasons why this translational gap, the so-called Valley of Death, exists, but sole reliance on biology that ignores biography contributes to this persistent challenge.

    CREDIT: LUCYNA KOCH/GETTY IMAGES

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