Research ArticleAsthma

DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment

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Science Translational Medicine  13 Feb 2019:
Vol. 11, Issue 479, eaao6451
DOI: 10.1126/scitranslmed.aao6451

Article Information

vol. 11 no. 479

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 21, 2017
  • Resubmitted June 15, 2018
  • Accepted for publication January 25, 2019
  • .

Author Information

  1. Ruth Saunders1,*,
  2. Himanshu Kaul1,2,*,,,
  3. Rachid Berair1,*,
  4. Sherif Gonem1,
  5. Amisha Singapuri1,
  6. Amanda J. Sutcliffe1,
  7. Latifa Chachi1,
  8. Michael S. Biddle1,
  9. Davinder Kaur1,
  10. Michelle Bourne1,
  11. Ian D. Pavord3,
  12. Andrew J. Wardlaw1,
  13. Salman H. Siddiqui1,
  14. Richard A. Kay4,§,
  15. Bindi S. Brook5,
  16. Rod H. Smallwood2,|| and
  17. Christopher E. Brightling1,,||
  1. 1University of Leicester, Leicester LE3 9QP, UK.
  2. 2University of Sheffield, Western Bank, Sheffield S1 4DP, UK.
  3. 3University of Oxford, Oxford OX3 7FZ, UK.
  4. 4Novartis Pharma AG, CH-4056 Basel, Switzerland.
  5. 5Nottingham University, Nottingham NG7 2RD, UK.
  1. Corresponding author. Email: ceb17{at}le.ac.uk (C.E.B.); himanshu.kaul{at}ubc.ca (H.K.)
  • * These authors contributed equally to this work.

  • Present address: University of British Columbia, Vancouver V6T 1Z3, Canada.

  • § Present address: Medpace Ltd, Stirling FK8 1JU, UK.

  • || Co-senior authors.

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