Research ArticleAutoimmunity

Dynamics of circulating TNF during adalimumab treatment using a drug-tolerant TNF assay

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Science Translational Medicine  30 Jan 2019:
Vol. 11, Issue 477, eaat3356
DOI: 10.1126/scitranslmed.aat3356

Article Information

vol. 11 no. 477

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 7, 2018
  • Resubmitted September 8, 2018
  • Accepted for publication December 19, 2018
  • .

Author Information

  1. Lea C. Berkhout1,*,
  2. Merel J. l’Ami2,*,
  3. Jill Ruwaard2,
  4. Margreet H. Hart1,
  5. Pleuni Ooijevaar-de Heer1,
  6. Karien Bloem1,
  7. Michael T. Nurmohamed2,3,
  8. Ronald F. van Vollenhoven2,3,4,
  9. Maarten Boers3,5,
  10. Daniel F. Alvarez6,
  11. Catherine H. Smith7,
  12. Gerrit J. Wolbink1,2 and
  13. Theo Rispens1,
  1. 1Department of Immunopathology, Sanquin Research, 1066 CX Amsterdam, Netherlands, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.
  2. 2Amsterdam Rheumatology and immunology Center, Reade, 1056 AB Amsterdam, Netherlands.
  3. 3Amsterdam Rheumatology and Immunology Center, Amsterdam UMC, VU University Medical Center, 1081 HV Amsterdam, Netherlands.
  4. 4Amsterdam Rheumatology and Immunology Center, Amsterdam UMC, Academic Medical Center, 1105 AZ Amsterdam, Netherlands.
  5. 5Department of Epidemiology and Biostatistics, VU University Medical Center, 1081 HV Amsterdam, Netherlands.
  6. 6Pfizer Inc., Collegeville, PA 19426, USA.
  7. 7St. John’s Institute of Dermatology, Division of Genetics and Molecular Medicine, Kings College London, SE1 9RT London, UK.
  1. Corresponding author. Email: t.rispens{at}sanquin.nl
  • * These authors contributed equally to this work.

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