Research ArticleMetabolism

An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

See allHide authors and affiliations

Science Translational Medicine  16 Jan 2019:
Vol. 11, Issue 475, eaau7975
DOI: 10.1126/scitranslmed.aau7975

Article Information

vol. 11 no. 475

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 16, 2018
  • Resubmitted October 8, 2018
  • Accepted for publication December 19, 2018
  • .

Author Information

  1. Caroline B. Kurtz1,*,
  2. Yves A. Millet1,,
  3. Marja K. Puurunen1,
  4. Mylène Perreault1,
  5. Mark R. Charbonneau1,
  6. Vincent M. Isabella1,
  7. Jonathan W. Kotula1,,
  8. Eugene Antipov1,
  9. Yossi Dagon1,
  10. William S. Denney2,
  11. David A. Wagner3,
  12. Kip A. West1,
  13. Andrew J. Degar4,
  14. Aoife M. Brennan1 and
  15. Paul F. Miller1
  1. 1Synlogic Inc., 301 Binney Street, Cambridge, MA 02142, USA.
  2. 2Human Predictions LLC, 649 Massachusetts Avenue Suite 6, Cambridge, MA 02139, USA.
  3. 3Metabolic Solutions Inc., 460 Amherst Street, Nashua, NH 03063, USA.
  4. 4Diversigen Inc., 1 Baylor Plaza, Houston, TX 77030, USA.
  1. *Corresponding author. Email: caroline{at}synlogictx.com
  • Present address: Kaleido Biosciences, 65 Hayden Avenue, Lexington, MA 02421, USA.

  • Present address: Caribou Biosciences, 2929 7th Street, Suite 105, Berkeley, CA 94710, USA.

Altmetric

Article usage

Article usage: January 2019 to August 2020

AbstractFullPdf
Jan 201998442483737
Feb 20191523545178
Mar 20191125565156
Apr 201961246895
May 2019410267120
Jun 201954314369
Jul 201961518082
Aug 20191005176117
Sep 201990919783
Oct 201996920367
Nov 201962622361
Dec 201944823381
Jan 20205228975
Feb 202028294103
Mar 202033324151
Apr 202041293209
May 202072268127
Jun 202028262108
Jul 2020820367
Aug 202039944

Stay Connected to Science Translational Medicine

Navigate This Article