Research ArticleAlzheimer’s Disease

Reduced non–rapid eye movement sleep is associated with tau pathology in early Alzheimer’s disease

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Science Translational Medicine  09 Jan 2019:
Vol. 11, Issue 474, eaau6550
DOI: 10.1126/scitranslmed.aau6550

Article Information

vol. 11 no. 474

PubMed: 
Print ISSN: 
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History: 
  • Received for publication July 6, 2018
  • Resubmitted October 24, 2018
  • Accepted for publication December 12, 2018

Author Information

  1. Brendan P. Lucey1,2,*,
  2. Austin McCullough3,
  3. Eric C. Landsness1,
  4. Cristina D. Toedebusch1,
  5. Jennifer S. McLeland1,
  6. Aiad M. Zaza3,
  7. Anne M. Fagan1,2,4,
  8. Lena McCue5,
  9. Chengjie Xiong5,
  10. John C. Morris1,2,4,
  11. Tammie L. S. Benzinger3,4 and
  12. David M. Holtzman1,2,4,*
  1. 1Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  2. 2Hope Center for Neurological Disorders, Washington University School of Medicine, St Louis, MO 63110, USA.
  3. 3Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  4. 4Knight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
  5. 5Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA.
  1. *Corresponding author. Email: luceyb{at}wustl.edu (B.P.L.); holtzman{at}wustl.edu (D.M.H.)

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