Research ArticleMalaria

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay

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Science Translational Medicine  02 Jan 2019:
Vol. 11, Issue 473, eaau3174
DOI: 10.1126/scitranslmed.aau3174

Article Information

vol. 11 no. 473

PubMed: 
Print ISSN: 
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History: 
  • Received for publication June 1, 2018
  • Resubmitted September 4, 2018
  • Accepted for publication December 5, 2018

Author Information

  1. Jerzy M. Dziekan1,
  2. Han Yu1,
  3. Dan Chen1,
  4. Lingyun Dai1,
  5. Grennady Wirjanata1,
  6. Andreas Larsson2,
  7. Nayana Prabhu1,
  8. Radoslaw M. Sobota3,4,
  9. Zbynek Bozdech1,* and
  10. Pär Nordlund1,3,2,*
  1. 1School of Biological Sciences, Nanyang Technological University, 637551, Singapore.
  2. 2Department of Oncology and Pathology, Karolinska Institutet, Stockholm 17177, Sweden.
  3. 3Institute of Molecular and Cell Biology, Functional Proteomics Laboratory, Agency for Science, Technology and Research (A*STAR), 138673, Singapore.
  4. 4Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), 138648, Singapore.
  1. *Corresponding author. Email: pnordlund{at}ntu.edu.sg (P.N.); zbozdech{at}ntu.edu.sg (Z.B.)

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Mar 201946437304
Apr 201916231131

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