Technical CommentsSepsis

Comment on “ALK is a therapeutic target for lethal sepsis”

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Science Translational Medicine  12 Dec 2018:
Vol. 10, Issue 471, eaar4321
DOI: 10.1126/scitranslmed.aar4321

Abstract

Physiologically relevant ALK (anaplastic lymphoma kinase) expression was not detected in human and mouse monocytes and macrophages, suggesting that the effects of bioactive compounds on stimulator of interferon genes (STING) activation may not depend on ALK.

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