Research ArticleGASTROINTESTINAL DISEASE

Cognitive impairments induced by necrotizing enterocolitis can be prevented by inhibiting microglial activation in mouse brain

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Science Translational Medicine  12 Dec 2018:
Vol. 10, Issue 471, eaan0237
DOI: 10.1126/scitranslmed.aan0237

Article Information

vol. 10 no. 471

PubMed: 
Print ISSN: 
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History: 
  • Received for publication February 27, 2017
  • Resubmitted April 21, 2018
  • Accepted for publication July 23, 2018
  • .

Author Information

  1. Diego F. Niño1,2,
  2. Qinjie Zhou1,2,
  3. Yukihiro Yamaguchi1,2,
  4. Laura Y. Martin1,2,
  5. Sanxia Wang1,2,
  6. William B. Fulton1,2,
  7. Hongpeng Jia1,2,
  8. Peng Lu1,2,
  9. Thomas Prindle Jr.1,2,
  10. Fan Zhang3,
  11. Joshua Crawford4,
  12. Zhipeng Hou5,
  13. Susumu Mori5,
  14. Liam L. Chen6,
  15. Andrew Guajardo6,
  16. Ali Fatemi7,
  17. Mikhail Pletnikov4,8,
  18. Rangaramanujam M. Kannan9,
  19. Sujatha Kannan10,
  20. Chhinder P. Sodhi1,2,* and
  21. David J. Hackam1,2,*
  1. 1Division of General Pediatric Surgery, Johns Hopkins University and Bloomberg Children’s Center, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
  2. 2Division of General Pediatric Surgery, Johns Hopkins University and Johns Hopkins Children’s Center, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
  3. 3Program of Immunology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  4. 4Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  5. 5Department of Biomedical Engineering and The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  6. 6Division of Neuropathology, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
  7. 7Departments of Neurology and Pediatrics, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, MD 21205, USA.
  8. 8Department of Molecular and Comparative Pathobiology and Solomon H. Snyder Department of Neuroscience, Johns Hopkins University and Johns Hopkins Children’s Center, Johns Hopkins Hospital, Baltimore, MD 21205, USA.
  9. 9Center for Nanomedicine, Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  10. 10Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  1. *Corresponding author. Email: dhackam1{at}jhmi.edu (D.J.H.); csodhi{at}jhmi.edu (C.P.S.)

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