Research ArticleNanomedicine
Cartilage-penetrating nanocarriers improve delivery and efficacy of growth factor treatment of osteoarthritis
- Brett C. Geiger1,2,
- Sheryl Wang1,2,
- Robert F. Padera Jr.3,
- Alan J. Grodzinsky1,4,5 and
- Paula T. Hammond2,6,*
- 1Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
- 2Koch Institute for Integrative Cancer Research, 500 Main Street, Cambridge, MA 02142, USA.
- 3Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, 45 Francis Street, Boston, MA 02115, USA.
- 4Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
- 5Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
- 6Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
- ↵*Corresponding author. Email: hammond{at}mit.edu
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Science Translational Medicine 28 Nov 2018:
Vol. 10, Issue 469, eaat8800
DOI: 10.1126/scitranslmed.aat8800
Vol. 10, Issue 469, eaat8800
DOI: 10.1126/scitranslmed.aat8800
Brett C. Geiger
Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.Koch Institute for Integrative Cancer Research, 500 Main Street, Cambridge, MA 02142, USA.
Sheryl Wang
Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.Koch Institute for Integrative Cancer Research, 500 Main Street, Cambridge, MA 02142, USA.
Robert F. Padera
Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, 45 Francis Street, Boston, MA 02115, USA.
Alan J. Grodzinsky
Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Paula T. Hammond
Koch Institute for Integrative Cancer Research, 500 Main Street, Cambridge, MA 02142, USA.Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
