Research ArticleTissue Engineering

Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc

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Science Translational Medicine  21 Nov 2018:
Vol. 10, Issue 468, eaau0670
DOI: 10.1126/scitranslmed.aau0670

Article Information

vol. 10 no. 468

PubMed: 
Print ISSN: 
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History: 
  • Received for publication May 4, 2018
  • Accepted for publication October 31, 2018
  • .

Author Information

  1. Sarah E. Gullbrand1,2,
  2. Beth G. Ashinsky1,2,3,*,
  3. Edward D. Bonnevie1,2,*,
  4. Dong Hwa Kim1,2,*,
  5. Julie B. Engiles4,
  6. Lachlan J. Smith1,2,5,
  7. Dawn M. Elliott6,
  8. Thomas P. Schaer4,
  9. Harvey E. Smith1,2,5, and
  10. Robert L. Mauck1,2,7,
  1. 1Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA.
  2. 2McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  3. 3School of Biomedical Sciences, Drexel University, Philadelphia, PA 19104, USA.
  4. 4Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19348, USA.
  5. 5Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
  6. 6Department of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
  7. 7Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
  1. Corresponding author. Email: lemauck{at}pennmedicine.upenn.edu (R.L.M.); harvey.smith{at}uphs.upenn.edu (H.E.S.)
  • * These authors contributed equally to this work.

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