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Research ArticleEMERGING INFECTIONS
Two recombinant human monoclonal antibodies that protect against lethal Andes hantavirus infection in vivo
- View ORCID ProfileJose L. Garrido1,2,
- Joseph Prescott3,4,
- View ORCID ProfileMario Calvo5,
- View ORCID ProfileFelipe Bravo1,2,
- Raymond Alvarez2,
- View ORCID ProfileAlexis Salas6,
- Raul Riquelme7,
- Maria L. Rioseco7,
- Brandi N. Williamson8,
- Elaine Haddock8,
- Heinz Feldmann8 and
- View ORCID ProfileMaria I. Barria1,*
- 1Faculty of Biological Science, Department of Microbiology, Center of Biotechnology, Universidad de Concepción, 4070386 Concepción, Chile.
- 2Ichor Biologics LLC, New York, NY 10065, USA.
- 3Arthropod and Infectious Disease Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
- 4Comparative Immunology of Risk Group-4 Viruses, Center for Biological Threats and Special Pathogens, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany.
- 5Institute of Medicine, Universidad Austral de Chile, Valdivia 5110566, Chile.
- 6Faculty of Biological Science, Department of Pharmacology, Universidad de Concepción, 4070386 Concepción, Chile.
- 7Hospital Regional Dr. Eduardo Schütz, Puerto Montt 5507798, Chile.
- 8Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
- ↵*Corresponding author. Email: mbarriac{at}udec.cl
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Science Translational Medicine 21 Nov 2018:
Vol. 10, Issue 468, eaat6420
DOI: 10.1126/scitranslmed.aat6420
Vol. 10, Issue 468, eaat6420
DOI: 10.1126/scitranslmed.aat6420
Jose L. Garrido
1Faculty of Biological Science, Department of Microbiology, Center of Biotechnology, Universidad de Concepción, 4070386 Concepción, Chile.
2Ichor Biologics LLC, New York, NY 10065, USA.
Joseph Prescott
3Arthropod and Infectious Disease Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
4Comparative Immunology of Risk Group-4 Viruses, Center for Biological Threats and Special Pathogens, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany.
Mario Calvo
5Institute of Medicine, Universidad Austral de Chile, Valdivia 5110566, Chile.
Felipe Bravo
1Faculty of Biological Science, Department of Microbiology, Center of Biotechnology, Universidad de Concepción, 4070386 Concepción, Chile.
2Ichor Biologics LLC, New York, NY 10065, USA.
Raymond Alvarez
2Ichor Biologics LLC, New York, NY 10065, USA.
Alexis Salas
6Faculty of Biological Science, Department of Pharmacology, Universidad de Concepción, 4070386 Concepción, Chile.
Raul Riquelme
7Hospital Regional Dr. Eduardo Schütz, Puerto Montt 5507798, Chile.
Maria L. Rioseco
7Hospital Regional Dr. Eduardo Schütz, Puerto Montt 5507798, Chile.
Brandi N. Williamson
8Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Elaine Haddock
8Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Heinz Feldmann
8Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.
Maria I. Barria
1Faculty of Biological Science, Department of Microbiology, Center of Biotechnology, Universidad de Concepción, 4070386 Concepción, Chile.
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