Research ArticleGUT MICROBIOTA

Clostridioides difficile uses amino acids associated with gut microbial dysbiosis in a subset of patients with diarrhea

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Science Translational Medicine  24 Oct 2018:
Vol. 10, Issue 464, eaam7019
DOI: 10.1126/scitranslmed.aam7019

Article Information

vol. 10 no. 464

PubMed: 
Print ISSN: 
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History: 
  • Received for publication January 5, 2017
  • Resubmitted November 17, 2017
  • Accepted for publication March 22, 2018
  • .

Author Information

  1. Eric J. Battaglioli1,*,
  2. Vanessa L. Hale2,3,*,
  3. Jun Chen4,
  4. Patricio Jeraldo2,
  5. Coral Ruiz-Mojica1,
  6. Bradley A. Schmidt1,
  7. Vayu M. Rekdal1,
  8. Lisa M. Till1,
  9. Lutfi Huq2,
  10. Samuel A. Smits5,
  11. William J. Moor1,
  12. Yava Jones-Hall6,
  13. Thomas Smyrk7,
  14. Sahil Khanna1,
  15. Darrell S. Pardi1,
  16. Madhusudan Grover1,
  17. Robin Patel8,
  18. Nicholas Chia2,
  19. Heidi Nelson2,
  20. Justin L. Sonnenburg5,
  21. Gianrico Farrugia9 and
  22. Purna C. Kashyap1,10,
  1. 1Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  2. 2Department of Surgery, Mayo Clinic, Rochester, MN, USA.
  3. 3Department of Veterinary Preventive Medicine, Ohio State University, Columbus, OH, USA.
  4. 4Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  5. 5Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.
  6. 6Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA.
  7. 7Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA.
  8. 8Department of Laboratory Medicine and Pathology, Division of Clinical Microbiology, Mayo Clinic, Rochester, MN, USA.
  9. 9Division of Gastroenterology, Mayo Clinic, Jacksonville, FL, USA.
  10. 10Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
  1. Corresponding author. Email: kashyap.purna{at}mayo.edu
    • * These authors contributed equally to this work.

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