Editors' ChoiceCancer

Self-defeating CAR-Ts protect leukemic cells

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Science Translational Medicine  17 Oct 2018:
Vol. 10, Issue 463, eaav3888
DOI: 10.1126/scitranslmed.aav3888

Abstract

Transfer of a CAR gene to a leukemic cell confers resistance to CAR-T cell therapy.

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