Research ArticleOsteoarthritis

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis

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Science Translational Medicine  10 Oct 2018:
Vol. 10, Issue 462, eaam7486
DOI: 10.1126/scitranslmed.aam7486

Article Information

vol. 10 no. 462

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  • Received for publication January 11, 2017
  • Accepted for publication September 20, 2018

Author Information

  1. Eun Kyung Song1,2,*,
  2. Jimin Jeon3,4,5,*,
  3. Dong Gil Jang1,
  4. Ha Eun Kim1,
  5. Hyo Jung Sim1,
  6. Keun Yeong Kwon1,
  7. Sofia Medina-Ruiz6,
  8. Hyun-Jun Jang1,
  9. Ah Reum Lee1,
  10. Jun Gi Rho7,
  11. Hyun-Shik Lee8,
  12. Seok Jung Kim9,
  13. Chan Young Park1,
  14. Kyungjae Myung2,
  15. Wook Kim7,
  16. Taejoon Kwon1,
  17. Siyoung Yang3,4,5, and
  18. Tae Joo Park1,2,
  1. 1School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
  2. 2Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.
  3. 3Department of Pharmacology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
  4. 4Department of Biomedical Sciences, Graduate School, Ajou University, Suwon 16499, Republic of Korea.
  5. 5CIRNO, Sungkyunkwan University, Suwon 16419, Republic of Korea.
  6. 6Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
  7. 7Department of Molecular Science and Technology, Ajou University, Suwon 16499, Republic of Korea.
  8. 8KNU-Center for Nonlinear Dynamics, CMRI, School of Life Sciences, BK21 Plus KNU Creative BioResearch Group, College of Natural Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
  9. 9Department of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
  1. Corresponding author. Email: parktj{at} (T.J.P.); yangsy{at} (S.Y.)
    • * These authors contributed equally to this work.


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