Editors' ChoiceNeuropsychiatric disorders

Astrocyte dysfunction and compulsive behavior

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Science Translational Medicine  03 Oct 2018:
Vol. 10, Issue 461, eaav3882
DOI: 10.1126/scitranslmed.aav3882

Abstract

Molecular, cellular, and circuit physiology studies identify a potential new therapeutic target for compulsive behavior disorders, involving dysfunctional neuron-astrocyte interactions within striatal microcircuits.

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