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p95HER2–T cell bispecific antibody for breast cancer treatment

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Science Translational Medicine  03 Oct 2018:
Vol. 10, Issue 461, eaat1445
DOI: 10.1126/scitranslmed.aat1445

Article Information

vol. 10 no. 461

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History: 
  • Received for publication January 29, 2018
  • Resubmitted June 15, 2018
  • Accepted for publication September 7, 2018
  • .

Author Information

  1. Irene Rius Ruiz1,2,*,
  2. Rocio Vicario1,*,
  3. Beatriz Morancho1,2,
  4. Cristina Bernadó Morales1,2,
  5. Enrique J. Arenas1,
  6. Sylvia Herter3,
  7. Anne Freimoser-Grundschober3,
  8. Jitka Somandin3,
  9. Johannes Sam3,
  10. Oliver Ast3,
  11. Águeda Martinez Barriocanal1,
  12. Antonio Luque1,
  13. Marta Escorihuela1,
  14. Ismael Varela1,
  15. Isabel Cuartas4,
  16. Paolo Nuciforo5,
  17. Roberta Fasani5,
  18. Vicente Peg2,6,
  19. Isabel Rubio6,
  20. Javier Cortés5,
  21. Violeta Serra1,2,
  22. Santiago Escriva-de-Romani5,6,
  23. Jeff Sperinde7,
  24. Ahmed Chenna7,
  25. Weidong Huang7,
  26. John Winslow7,
  27. Joan Albanell2,8,9,10,
  28. Joan Seoane2,4,11,12,
  29. Maurizio Scaltriti13,
  30. Jose Baselga14,
  31. Josep Tabernero2,5,6,
  32. Pablo Umana3,
  33. Marina Bacac3,
  34. Cristina Saura5,6,,
  35. Christian Klein3, and
  36. Joaquín Arribas1,2,11,12,,
  1. 1Preclinical Research Program, Vall d’Hebron Institute of Oncology (VHIO), 08035 Barcelona, Spain.
  2. 2Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 08035 Barcelona, Spain.
  3. 3Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development, Wagistrasse 18, 8952 Schlieren, Switzerland.
  4. 4Translational Research Program, VHIO, 08035 Barcelona, Spain.
  5. 5Clinical Research Program, VHIO, 08035 Barcelona, Spain.
  6. 6Vall d’Hebron University Hospital, 08035 Barcelona, Spain.
  7. 7Monogram Biosciences, Laboratory Corporation of America Holdings, South San Francisco, CA 94080, USA.
  8. 8Cancer Research Program, IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.
  9. 9Medical Oncology Service, Hospital del Mar, 08003 Barcelona, Spain.
  10. 10Universitat Pompeu Fabra, 08003 Barcelona, Spain.
  11. 11Department of Biochemistry and Molecular Biology, Universitat Autónoma de Barcelona, Campus de la UAB, 08193 Bellaterra, Spain.
  12. 12Institució Catalana de Recerca i Estudis Avançats, 08010 Barcelona, Spain.
  13. 13Department of Pathology, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  14. 14Department of Medicine, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  1. Corresponding author. Email: jarribas{at}vhio.net
    • * These authors contributed equally to this work.

    • These authors jointly supervised this work.

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