Research ArticleDrug Development

Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections

See allHide authors and affiliations

Science Translational Medicine  26 Sep 2018:
Vol. 10, Issue 460, eaat7520
DOI: 10.1126/scitranslmed.aat7520

Article Information

vol. 10 no. 460

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 30, 2018
  • Accepted for publication September 6, 2018
  • .

Author Information

  1. Christopher H. Goss1,2,
  2. Yukihiro Kaneko3,
  3. Lisa Khuu4,
  4. Gail D. Anderson5,
  5. Sumedha Ravishankar4,
  6. Moira L. Aitken1,
  7. Noah Lechtzin6,
  8. Guolin Zhou7,
  9. Daniel M. Czyz8,
  10. Kathryn McLean9,
  11. Oyebode Olakanmi10,
  12. Howard A. Shuman8,
  13. Mary Teresi11,
  14. Ellen Wilhelm1,
  15. Ellen Caldwell1,
  16. Stephen J. Salipante9,
  17. Douglas B. Hornick11,
  18. Richard J. Siehnel4,
  19. Lev Becker7,
  20. Bradley E. Britigan12 and
  21. Pradeep K. Singh4,1,*
  1. 1Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
  2. 2Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195, USA.
  3. 3Department of Bacteriology, Osaka City University School of Medicine, Osaka 545-0051, Japan.
  4. 4Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195, USA.
  5. 5Department of Pharmacy, University of Washington School of Pharmacy, Seattle, WA 98195, USA.
  6. 6Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  7. 7Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA.
  8. 8Department of Microbiology, The University of Chicago, Chicago, IL 60637, USA.
  9. 9Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
  10. 10University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
  11. 11Departments of Medicine and Pediatrics, University of Iowa, Iowa City, IA 52242, USA.
  12. 12Department of Medicine, University of Nebraska School of Medicine, Omaha, NE 68105, USA.
  1. *Corresponding author. Email: singhpr{at}uw.edu

Altmetric

Article usage

Article usage: September 2018 to September 2019

AbstractFullPdf
Sep 20180228961231
Oct 2018134662031042
Nov 2018137212574
Dec 20189073443
Jan 20193926554
Feb 20192724752
Mar 20191785251
Apr 20191904047
May 20191643142
Jun 20191393740
Jul 20191343940
Aug 20191553520
Sep 2019852114