Research ArticleProgeria

Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome

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Science Translational Medicine  26 Sep 2018:
Vol. 10, Issue 460, eaat7163
DOI: 10.1126/scitranslmed.aat7163

Article Information

vol. 10 no. 460

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 27, 2018
  • Accepted for publication September 7, 2018
  • .

Author Information

  1. Paul H. Kim1,
  2. Jennings Luu1,
  3. Patrick Heizer1,
  4. Yiping Tu1,
  5. Thomas A. Weston1,
  6. Natalie Chen1,
  7. Christopher Lim1,
  8. Robert L. Li1,
  9. Po-Yu Lin2,
  10. James C. Y. Dunn2,
  11. Didier Hodzic3,
  12. Stephen G. Young1,4,* and
  13. Loren G. Fong1,*
  1. 1Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  2. 2Department of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, USA.
  3. 3Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  4. 4Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  1. *Corresponding author. Email: lfong{at}mednet.ucla.edu (L.G.F.); sgyoung{at}mednet.ucla.edu (S.G.Y.)

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