Editors' ChoiceTransplantation

Graft-versus-host disease: Tread carefully on T cell suppression

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Science Translational Medicine  12 Sep 2018:
Vol. 10, Issue 458, eaav0338
DOI: 10.1126/scitranslmed.aav0338

Abstract

CD28-targeting synergizes with mTOR inhibition to prevent graft-versus-host disease but increases infection-related fatality in nonhuman primates.

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