Research ArticleLUNG VENTILATION

Preventing loss of mechanosensation by the nuclear membranes of alveolar cells reduces lung injury in mice during mechanical ventilation

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Science Translational Medicine  29 Aug 2018:
Vol. 10, Issue 456, eaam7598
DOI: 10.1126/scitranslmed.aam7598

Article Information

vol. 10 no. 456

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History: 
  • Received for publication January 16, 2017
  • Resubmitted August 30, 2017
  • Accepted for publication January 25, 2018
  • .

Author Information

  1. Inés López-Alonso1,2,3,4,
  2. Jorge Blázquez-Prieto1,2,3,4,
  3. Laura Amado-Rodríguez1,3,4,
  4. Adrián González-López4,5,
  5. Aurora Astudillo6,7,
  6. Manuel Sánchez8,
  7. Covadonga Huidobro1,3,4,
  8. Cecilia López-Martínez2,3,
  9. Claudia C. dos Santos9 and
  10. Guillermo M. Albaiceta1,2,3,4,*
  1. 1Área del Corazón, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
  2. 2Departamento de Biología Funcional, Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, 33005 Oviedo, Spain.
  3. 3Instituto de Investigación Sanitaria del Principado de Asturias, 33011 Oviedo, Spain.
  4. 4Centro de Investigación Biomédica En Red–Enfermedades Respiratorias, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  5. 5Department of Anesthesiology and Operative Intensive Care Medicine, Charité Universitätsmedizin, 10117 Berlin, Germany.
  6. 6Servicio de Anatomía Patológica, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
  7. 7Departamento de Cirugía y Especialidades Médicoquirúrgicas, Universidad de Oviedo, 33005 Oviedo, Spain.
  8. 8Área de Farmacología, Departamento de Medicina, Universidad de Oviedo, 33005 Oviedo, Spain.
  9. 9Interdepartmental Division of Critical Care, Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, University of Toronto, Toronto, Ontario M5B 1WB, Canada.
  1. *Corresponding author. Email: guillermo.muniz{at}sespa.es

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