Tooth stem cells regenerate smiles
Dental pulp necrosis is one of the most common pathological conditions that results in tooth loss. However, regeneration of functional dental pulp has proved difficult. In a new study, Xuan et al. implanted ex vivo expanded autologous tooth stem cells from deciduous teeth in two animal models and in human patients. They demonstrated regeneration of dental pulp containing an odontoblast layer, blood vessels, and nerves in the implanted teeth and rescue of sensation to stimuli such as temperature. This work suggests that implantation of tooth stem cells can provide partial recovery of teeth injured by trauma.
- Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works
http://www.sciencemag.org/about/science-licenses-journal-article-reuse
This is an article distributed under the terms of the Science Journals Default License.
