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Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone

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Science Translational Medicine  01 Aug 2018:
Vol. 10, Issue 452, eaao5726
DOI: 10.1126/scitranslmed.aao5726

Article Information

vol. 10 no. 452

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History: 
  • Received for publication August 7, 2017
  • Resubmitted January 16, 2018
  • Accepted for publication June 19, 2018
  • .

Author Information

  1. Eleonora Dondossola1,
  2. Stephanie Alexander1,*,
  3. Boris M. Holzapfel2,3,
  4. Stefano Filippini1,
  5. Michael W. Starbuck1,
  6. Robert M. Hoffman4,
  7. Nora Navone1,
  8. Elena M. De-Juan-Pardo2,
  9. Christopher J. Logothetis1,
  10. Dietmar W. Hutmacher2,5 and
  11. Peter Friedl1,6,7,
  1. 1David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
  2. 2Centre in Regenerative Medicine, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), 60 Musk Avenue, Kelvin Grove, Brisbane, Queensland 4059, Australia.
  3. 3Orthopaedic Center for Musculoskeletal Research, University of Würzburg, Brettreichstraße 11, 97074 Würzburg, Germany.
  4. 4Department of Surgery, University of California, San Diego and AntiCancer Inc., 7917 Ostrow Street, San Diego, CA 92111, USA.
  5. 5ARC Centre in Additive Biomanufacturing, QUT, 60 Musk Avenue, Kelvin Grove, Brisbane, Queensland 4059, Australia.
  6. 6Radboud University Nijmegen, Nijmegen, Netherlands.
  7. 7Cancer Genomics Centre (CGC.nl), 3584 Utrecht, Netherlands.
  1. Corresponding author. Email: pfriedl{at}mdanderson.org
  • * Present address: European Molecular Biology Laboratory, Cell Biology and Biophysics Unit, 69117 Heidelberg, Germany.

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