Research ArticleCancer

Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

See allHide authors and affiliations

Science Translational Medicine  25 Jul 2018:
Vol. 10, Issue 451, eaat3504
DOI: 10.1126/scitranslmed.aat3504

Article Information

vol. 10 no. 451

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 20, 2018
  • Accepted for publication May 30, 2018
  • .

Author Information

  1. Kieren D. Marini1,2,
  2. David R. Croucher3,4,5,
  3. Rachael A. McCloy3,
  4. Vijesh Vaghjiani1,
  5. Alvaro Gonzalez-Rajal3,
  6. Jordan F. Hastings3,
  7. Venessa Chin3,6,
  8. Anette Szczepny1,
  9. Kaja Kostyrko7,
  10. Cesar Marquez7,
  11. W. Samantha N. Jayasekara1,
  12. Muhammad Alamgeer1,2,8,
  13. Vishal Boolell1,8,
  14. Jeremy Z. R. Han3,
  15. Todd Waugh1,
  16. Hong Ching Lee3,
  17. Samantha R. Oakes3,4,
  18. Beena Kumar9,
  19. Craig A. Harrison1,2,
  20. Mark P. Hedger1,2,
  21. Nirmal Lorensuhewa10,
  22. Badia Kita10,
  23. Ross Barrow10,
  24. Bruce W. Robinson11,
  25. David M. de Kretser1,2,10,
  26. Jianmin Wu3,4,12,13,
  27. Vinod Ganju1,2,
  28. E. Alejandro Sweet-Cordero7,
  29. Andrew Burgess3,14,
  30. Luciano G. Martelotto2,15,
  31. Fernando J. Rossello16,17,
  32. Jason E. Cain1,* and
  33. D. Neil Watkins3,4,18,*
  1. 1Hudson Institute of Medical Research, Clayton, Victoria 3168, Australia.
  2. 2Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria 3800, Australia.
  3. 3The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.
  4. 4St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales Sydney, Darlinghurst, New South Wales 2010, Australia.
  5. 5School of Medicine, University College Dublin, Belfield, Dublin D04 V1W8, Ireland.
  6. 6Department of Medical Oncology, St. Vincent’s Hospital, Darlinghurst, New South Wales 2010, Australia.
  7. 7Department of Pediatrics, University of California San Francisco, San Francisco, CA 94158, USA.
  8. 8Department of Medical Oncology, Monash Medical Centre, East Bentleigh, Victoria 3165, Australia.
  9. 9Department of Pathology, Monash Medical Centre, Clayton, Victoria 3168, Australia.
  10. 10Paranta Biosciences Limited, Melbourne, Victoria 3004, Australia.
  11. 11School of Medicine and Pharmacology, Queen Elizabeth II Medical Centre Unit, University of Western Australia, Crawley, Western Australia 6009, Australia.
  12. 12Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Beijing, China.
  13. 13Center for Cancer Bioinformatics, Peking University Cancer Hospital and Institute, Hai-Dian District, Beijing 100142, China.
  14. 14ANZAC Research Institute, Concord, New South Wales 2139, Australia.
  15. 15Center for Cancer Research, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria 3000, Australia.
  16. 16Australian Regenerative Medicine Institute, Clayton, Victoria 3800, Australia.
  17. 17Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australia.
  18. 18Department of Thoracic Medicine, St. Vincent’s Hospital, Darlinghurst, New South Wales 2010, Australia.
  1. *Corresponding author. Email: n.watkins{at}garvan.org.au (D.N.W.); jason.cain{at}hudson.org.au (J.E.C.)

Altmetric

Article usage

Article usage: July 2018 to June 2021

AbstractFullPdf
Jul 20184195527296
Aug 2018882192182
Sep 20182635377
Oct 20183826165
Nov 20189295048
Dec 20184604026
Jan 20191473523
Feb 20191112718
Mar 20191153621
Apr 20191594941
May 20191025022
Jun 2019964928
Jul 201917011323
Aug 20191528263
Sep 20191510132
Oct 20193318056
Nov 2019516863
Dec 20194415361
Jan 2020116356
Feb 2020428240
Mar 202015219828
Apr 2020313846
May 2020415560
Jun 2020413243
Jul 202037641
Aug 2020149943
Sep 202047737
Oct 202059653
Nov 2020321944
Dec 202039940
Jan 202167740
Feb 2021210842
Mar 2021410644
Apr 2021145125
May 202138874
Jun 202113318

Stay Connected to Science Translational Medicine

Navigate This Article