Research ArticleHepatitis C Virus

Modeling of patient virus titers suggests that availability of a vaccine could reduce hepatitis C virus transmission among injecting drug users

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Science Translational Medicine  11 Jul 2018:
Vol. 10, Issue 449, eaao4496
DOI: 10.1126/scitranslmed.aao4496

Article Information

vol. 10 no. 449

Print ISSN: 
Online ISSN: 
  • Received for publication August 21, 2017
  • Resubmitted February 24, 2018
  • Accepted for publication June 22, 2018

Author Information

  1. Marian Major1,*,
  2. Alexander Gutfraind2,3,,
  3. Louis Shekhtman2,4,,
  4. Qingwen Cui1,
  5. Alla Kachko1,
  6. Scott J. Cotler2,
  7. Behzad Hajarizadeh5,
  8. Rachel Sacks-Davis6,7,
  9. Kimberly Page8,
  10. Basmattee Boodram3 and
  11. Harel Dahari2,*
  1. 1Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA.
  2. 2Program for Experimental and Theoretical Modeling, Division of Hepatology, Department of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
  3. 3Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL 60612, USA.
  4. 4Department of Physics, Bar-Ilan University, Ramat Gan 52990, Israel.
  5. 5The Kirby Institute, University of New South Wales, Sydney, New South Wales 2052, Australia.
  6. 6Disease Elimination Program, Burnet Institute, Melbourne, Victoria 3004, Australia.
  7. 7Department of Medicine, University of Melbourne, Parkville, Victoria 3010, Australia.
  8. 8Division of Epidemiology, Biostatistics and Preventive Medicine, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
  1. *Corresponding author. Email: marian.major{at} (M.M.); hdahari{at} (H.D.)
    • These authors contributed equally to this work.


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