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Research ArticleMalaria
Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria
- View ORCID ProfileHyun Jae Lee1,*,
- View ORCID ProfileAthina Georgiadou2,
- Michael Walther3,
- View ORCID ProfileDavis Nwakanma3,
- Lindsay B. Stewart4,
- Michael Levin2,
- View ORCID ProfileThomas D. Otto5,†,‡,
- View ORCID ProfileDavid J. Conway4,†,
- Lachlan J. Coin1,† and
- View ORCID ProfileAubrey J. Cunnington2,§
- 1Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.
- 2Section of Paediatrics, Imperial College, London W2 1PG, UK.
- 3Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia.
- 4Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
- 5Wellcome Trust Sanger Centre, Hinxton, Cambridge CB10 1SA, UK.
- ↵§Corresponding author. Email: a.cunnington{at}imperial.ac.uk
↵* Present address: Queensland Institute of Medical Research Berghofer Medical Research Institute, Locked Bag 2000, Royal Brisbane Hospital, Queensland 4029, Australia.
↵† These authors contributed equally to this work.
↵‡ Present address: Centre of Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
See allHide authors and affiliations
Science Translational Medicine 27 Jun 2018:
Vol. 10, Issue 447, eaar3619
DOI: 10.1126/scitranslmed.aar3619
Vol. 10, Issue 447, eaar3619
DOI: 10.1126/scitranslmed.aar3619
Hyun Jae Lee
1Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.
Athina Georgiadou
2Section of Paediatrics, Imperial College, London W2 1PG, UK.
Michael Walther
3Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia.
Davis Nwakanma
3Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia.
Lindsay B. Stewart
4Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Michael Levin
2Section of Paediatrics, Imperial College, London W2 1PG, UK.
Thomas D. Otto
5Wellcome Trust Sanger Centre, Hinxton, Cambridge CB10 1SA, UK.
David J. Conway
4Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Lachlan J. Coin
1Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.
Aubrey J. Cunnington
2Section of Paediatrics, Imperial College, London W2 1PG, UK.
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