Research ArticleMalaria

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

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Science Translational Medicine  27 Jun 2018:
Vol. 10, Issue 447, eaar3619
DOI: 10.1126/scitranslmed.aar3619

Article Information

vol. 10 no. 447

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  • Received for publication October 31, 2017
  • Resubmitted January 31, 2018
  • Accepted for publication June 8, 2018
  • .

Author Information

  1. Hyun Jae Lee1,*,
  2. Athina Georgiadou2,
  3. Michael Walther3,
  4. Davis Nwakanma3,
  5. Lindsay B. Stewart4,
  6. Michael Levin2,
  7. Thomas D. Otto5,,,
  8. David J. Conway4,,
  9. Lachlan J. Coin1, and
  10. Aubrey J. Cunnington2,§
  1. 1Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.
  2. 2Section of Paediatrics, Imperial College, London W2 1PG, UK.
  3. 3Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia.
  4. 4Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
  5. 5Wellcome Trust Sanger Centre, Hinxton, Cambridge CB10 1SA, UK.
  1. §Corresponding author. Email: a.cunnington{at}
    • * Present address: Queensland Institute of Medical Research Berghofer Medical Research Institute, Locked Bag 2000, Royal Brisbane Hospital, Queensland 4029, Australia.

    • These authors contributed equally to this work.

    • Present address: Centre of Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.


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