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Statins enhance efficacy of venetoclax in blood cancers

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Science Translational Medicine  13 Jun 2018:
Vol. 10, Issue 445, eaaq1240
DOI: 10.1126/scitranslmed.aaq1240

Article Information

vol. 10 no. 445

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 3, 2017
  • Accepted for publication May 11, 2018
  • .

Author Information

  1. J. Scott Lee1,*,
  2. Andrew Roberts2,,,
  3. Dennis Juarez1,
  4. Thanh-Trang T. Vo1,§,
  5. Shruti Bhatt3,
  6. Lee-or Herzog1,
  7. Sharmila Mallya1,
  8. Richard J. Bellin2,
  9. Suresh K. Agarwal2,
  10. Ahmed Hamed Salem2,4,
  11. Tu Xu2,
  12. Jia Jia2,
  13. Lingxiao Li5,
  14. John R. Hanna3,
  15. Matthew S. Davids3,
  16. Angela G. Fleischman6,
  17. Susan O’Brien6,
  18. Lloyd T. Lam2,
  19. Joel D. Leverson2,
  20. Anthony Letai3,
  21. Jonathan H. Schatz5 and
  22. David A. Fruman1,
  1. 1Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697, USA.
  2. 2Oncology Development, AbbVie Inc., North Chicago, IL 60064, USA.
  3. 3Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  4. 4Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.
  5. 5Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  6. 6Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA.
  1. Corresponding author. Email: dfruman{at}uci.edu (D.A.F.); awroberts{at}comcast.net (A.R.)
  • * Present address: Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.

  • Present address: PRA Health Sciences, Raleigh, NC 27612, USA.

  • § Present address: VelosBio, San Diego, CA 92121, USA.

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Article usage: June 2018 to September 2019

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Jun 20187518324541
Jul 201873745103
Aug 201839514074
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Dec 20181704451
Jan 20191905155
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Aug 201958349
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