Research ArticleInfectious Disease
A live vaccine rapidly protects against cholera in an infant rabbit model
- Troy P. Hubbard1,2,
- Gabriel Billings1,2,
- Tobias Dörr1,2,*,
- Brandon Sit1,2,
- Alyson R. Warr1,2,
- Carole J. Kuehl1,2,
- Minsik Kim1,2,†,
- Fernanda Delgado2,3,
- John J. Mekalanos1,
- Joseph A. Lewnard4 and
- Matthew K. Waldor1,2,3,5,‡
- 1Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
- 2Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
- 3Howard Hughes Medical Institute, Boston, MA 02115, USA.
- 4Center for Communicable Disease Dynamics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
- 5Department of Immunology and Infectious Disease, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
- ↵‡Corresponding author. Email: mwaldor{at}research.bwh.harvard.edu
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Science Translational Medicine 13 Jun 2018:
Vol. 10, Issue 445, eaap8423
DOI: 10.1126/scitranslmed.aap8423
Vol. 10, Issue 445, eaap8423
DOI: 10.1126/scitranslmed.aap8423
Troy P. Hubbard
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
Gabriel Billings
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
Tobias Dörr
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
Brandon Sit
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
Alyson R. Warr
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
Carole J. Kuehl
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
Minsik Kim
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.
Fernanda Delgado
Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.Howard Hughes Medical Institute, Boston, MA 02115, USA.
John J. Mekalanos
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
Joseph A. Lewnard
Center for Communicable Disease Dynamics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Matthew K. Waldor
Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, MA 02115, USA.Howard Hughes Medical Institute, Boston, MA 02115, USA.Department of Immunology and Infectious Disease, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
