Research ArticlePulmonary Arterial Hypertension

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension

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Science Translational Medicine  13 Jun 2018:
Vol. 10, Issue 445, eaap7294
DOI: 10.1126/scitranslmed.aap7294

Article Information

vol. 10 no. 445

PubMed: 
Print ISSN: 
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History: 
  • Received for publication August 21, 2017
  • Accepted for publication May 23, 2018

Author Information

  1. Andriy O. Samokhin1,
  2. Thomas Stephens1,
  3. Bradley M. Wertheim1,2,
  4. Rui-Sheng Wang3,
  5. Sara O. Vargas4,
  6. Lai-Ming Yung5,
  7. Minwei Cao1,
  8. Marcel Brown1,
  9. Elena Arons1,
  10. Paul B. Dieffenbach2,
  11. Jason G. Fewell6,
  12. Majed Matar6,
  13. Frederick P. Bowman1,
  14. Kathleen J. Haley2,
  15. George A. Alba7,
  16. Stefano M. Marino8,9,
  17. Rahul Kumar10,
  18. Ivan O. Rosas2,
  19. Aaron B. Waxman2,
  20. William M. Oldham2,
  21. Dinesh Khanna11,
  22. Brian B. Graham10,
  23. Sachiko Seo12,
  24. Vadim N. Gladyshev8,
  25. Paul B. Yu5,
  26. Laura E. Fredenburgh2,
  27. Joseph Loscalzo1,5,
  28. Jane A. Leopold5 and
  29. Bradley A. Maron5,*
  1. 1Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.
  2. 2Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.
  3. 3Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.
  4. 4Department of Pathology, Boston Children’s Hospital, Boston, MA 02115, USA.
  5. 5Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.
  6. 6Celsion Corporation, Lawrenceville, NJ 08648, USA.
  7. 7Department of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
  8. 8Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.
  9. 9Department of Biotechnology, Akdeniz University, Konyaaltı, Antalya 07058, Turkey.
  10. 10Program in Translational Lung Research, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  11. 11Division of Rheumatology, University of Michigan Scleroderma Program, Ann Arbor, MI 48109, USA.
  12. 12Department of Hematology and Oncology, National Cancer Research Center East, Kashiwa-shi, Chiba-ken 277-8577, Japan.
  1. *Corresponding author. Email: bmaron{at}bwh.harvard.edu

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Jul 201861055104
Aug 20183176856
Sep 20181865844
Oct 20181956239
Nov 20181743925
Dec 20182413322
Jan 20191605024
Feb 20191522418
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