30 May 2018
Vol 10, Issue 443

About The Cover

Cover image expansion

ONLINE COVER A Leg Up for Neuroprosthetics. Traditional prostheses do not convey sensory feedback, making it difficult for amputees to precisely control artificial limbs. Here we see a powered ankle-foot prosthesis worn by a subject with a below-knee amputation (Clites et al.). Two agonist-antagonist myoneural interfaces (AMIs)–muscle-tendon pairs–were created in the subject's residual limb during his amputation procedure. When these AMIs were connected via electrodes to his prosthesis, the subject could sense and control the movement of the joints of his prosthesis by voluntarily contracting the AMIs. The subject exhibited natural reflexive behaviors not seen in four subjects with traditional amputations (lacking AMIs). By restoring natural sensation to prosthetic joints, AMIs could improve prosthetic control. [CREDIT: CLITES ET AL./SCIENCE TRANSLATIONAL MEDICINE]