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Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma

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Science Translational Medicine  16 May 2018:
Vol. 10, Issue 441, eaao4680
DOI: 10.1126/scitranslmed.aao4680

Article Information

vol. 10 no. 441

PubMed: 
Print ISSN: 
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History: 
  • Received for publication July 24, 2017
  • Resubmitted January 18, 2018
  • Accepted for publication April 20, 2018
  • .

Author Information

  1. Timothy L. Lochmann1,
  2. Krista M. Powell1,
  3. Jungoh Ham1,
  4. Konstantinos V. Floros1,
  5. Daniel A. R. Heisey1,
  6. Richard I. J. Kurupi1,
  7. Marissa L. Calbert1,
  8. Maninderjit S. Ghotra1,
  9. Patricia Greninger2,
  10. Mikhail Dozmorov3,
  11. Madhu Gowda4,
  12. Andrew J. Souers5,
  13. C. Patrick Reynolds6,
  14. Cyril H. Benes2,*, and
  15. Anthony C. Faber1,*,
  1. 1Virginia Commonwealth University Philips Institute, School of Dentistry and Massey Cancer Center, Richmond, VA 23298, USA.
  2. 2Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  3. 3Department of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298, USA.
  4. 4Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Children’s Hospital of Richmond at Virginia Commonwealth University, Richmond, VA 23298, USA.
  5. 5AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
  6. 6Cancer Center, Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX 79430, USA.
  1. Corresponding author. Email: acfaber{at}vcu.edu (A.C.F.); cbenes{at}mgh.harvard.edu (C.H.B.)
    • * These authors contributed equally to this work.

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