Research ArticleFETAL IMMUNITY

Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-γ and TNF-α

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Science Translational Medicine  25 Apr 2018:
Vol. 10, Issue 438, eaan2263
DOI: 10.1126/scitranslmed.aan2263

Article Information

vol. 10 no. 438

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 14, 2017
  • Resubmitted December 13, 2017
  • Accepted for publication April 5, 2018
  • .

Author Information

  1. Michela Frascoli1,2,
  2. Lacy Coniglio1,2,
  3. Russell Witt1,2,
  4. Cerine Jeanty1,2,
  5. Shannon Fleck-Derderian3,
  6. Dana E. Myers4,
  7. Tzong-Hae Lee5,
  8. Sheila Keating5,
  9. Michael P. Busch5,
  10. Philip J. Norris5,
  11. Qizhi Tang2,
  12. Giovanna Cruz6,
  13. Lisa F. Barcellos6,
  14. Nardhy Gomez-Lopez7,8,9,
  15. Roberto Romero7,10,11,12 and
  16. Tippi C. MacKenzie1,2,13,*
  1. 1Eli and Edythe Broad Center of Regeneration Medicine, University of California, San Francisco, CA 94143, USA.
  2. 2Department of Surgery, University of California, San Francisco, CA 94143, USA.
  3. 3Department of Pediatrics, University of California, San Francisco, CA 94143, USA.
  4. 4Obstetrics and Gynecology, University of California, San Francisco, CA 94143, USA.
  5. 5Blood Systems Research Institute, San Francisco, CA 94118, USA.
  6. 6Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, CA 94720, USA.
  7. 7Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)/National Institutes of Health (NIH)/U.S. Department of Health and Human Services (DHHS), Bethesda, MD 20892, USA.
  8. 8Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
  9. 9Department of Microbiology, Immunology, and Biochemistry, Wayne State University School of Medicine, Detroit, MI 48201, USA.
  10. 10Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109, USA.
  11. 11Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI 48824, USA.
  12. 12Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI 48201, USA.
  13. 13Center for Maternal-Fetal Precision Medicine, University of California, San Francisco, CA 94143, USA.
  1. *Corresponding author. Email: tippi.mackenzie{at}ucsf.edu

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