04 April 2018
Vol 10, Issue 435

About The Cover

Cover image expansion

ONLINE COVER Illuminating New Treatments for Blinding Diseases. Shown is a retinal fundus photograph of the retina of a patient with the blinding disease advanced dry age-related macular degeneration (AMD). This patient underwent minimally invasive surgery to receive a tissue-engineered retinal pigment epithelium monolayer developed by Kashani et al. with the goal of replacing retinal cells lost due to AMD. The image shows the tissue engineered implant on the patient's retina 90 days after surgery. Kashani et al. have implanted four patients with AMD so far, and the implant was found to be safe and well tolerated for up to 1 year after surgery. [CREDIT: KASHANI ET AL./SCIENCE TRANSLATIONAL MEDICINE]