Research ArticleInfection

Integrated molecular imaging reveals tissue heterogeneity driving host-pathogen interactions

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Science Translational Medicine  14 Mar 2018:
Vol. 10, Issue 432, eaan6361
DOI: 10.1126/scitranslmed.aan6361

Article Information

vol. 10 no. 432

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History: 
  • Received for publication May 11, 2017
  • Resubmitted November 5, 2017
  • Accepted for publication February 5, 2018
  • .

Author Information

  1. James E. Cassat1,2,*,
  2. Jessica L. Moore3,4,5,*,
  3. Kevin J. Wilson6,
  4. Zach Stark6,
  5. Boone M. Prentice3,5,
  6. Raf Van de Plas3,5,7,
  7. William J. Perry3,4,
  8. Yaofang Zhang3,5,
  9. John Virostko6,,
  10. Daniel C. Colvin6,
  11. Kristie L. Rose3,5,
  12. Audra M. Judd3,
  13. Michelle L. Reyzer3,
  14. Jeffrey M. Spraggins3,4,5,
  15. Caroline M. Grunenwald2,
  16. John C. Gore5,6,8,
  17. Richard M. Caprioli3,4,5,9 and
  18. Eric P. Skaar2,10,
  1. 1Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  2. 2Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  3. 3Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN 37232, USA.
  4. 4Department of Chemistry, Vanderbilt University, Nashville, TN 37232, USA.
  5. 5Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA.
  6. 6Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN 37232, USA.
  7. 7Delft Center for Systems and Control, Delft University of Technology, Delft, Netherlands.
  8. 8Departments of Radiology and Radiologic Sciences, Biomedical Engineering, Molecular Physiology and Biophysics, and Physics and Astronomy, Vanderbilt University, Nashville, TN 37232, USA.
  9. 9Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  10. 10U.S. Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, 37232, USA.
  1. Corresponding author. Email: eric.skaar{at}vanderbilt.edu
    • * These authors contributed equally to this work.

    • Present address: Department of Diagnostic Medicine, Dell Medical School, University of Texas at Austin, Austin, TX 78705, USA.

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