Research ArticleCancer

Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy

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Science Translational Medicine  28 Feb 2018:
Vol. 10, Issue 430, eaao2731
DOI: 10.1126/scitranslmed.aao2731

Article Information

vol. 10 no. 430

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 5, 2017
  • Resubmitted October 31, 2017
  • Accepted for publication December 13, 2017
  • .

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Author Information

  1. Serena Pellegatta1,2,
  2. Barbara Savoldo2,3,
  3. Natalia Di Ianni1,
  4. Cristina Corbetta1,
  5. Yuhui Chen2,
  6. Monica Patané4,
  7. Chuang Sun2,
  8. Bianca Pollo4,
  9. Soldano Ferrone5,
  10. Francesco DiMeco6,
  11. Gaetano Finocchiaro1 and
  12. Gianpietro Dotti2,7,*
  1. 1Unit of Molecular Neuro-Oncology, Fondazione Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Istituto Neurologico C. Besta, Milan 20133, Italy.
  2. 2Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.
  3. 3Department of Pediatrics, University of North Carolina, Chapel Hill, NC 27599, USA.
  4. 4Unit of Neuropathology, Fondazione IRCCS Istituto Neurologico C. Besta, Milan 20133, Italy.
  5. 5Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  6. 6Department of Neuro-Surgery, Fondazione IRCCS Istituto Neurologico C. Besta, Milan 20133, Italy.
  7. 7Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.
  1. *Corresponding author. Email: gdotti{at}med.unc.edu

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