Research ArticleTuberculosis

Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe

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Science Translational Medicine  28 Feb 2018:
Vol. 10, Issue 430, eaam6310
DOI: 10.1126/scitranslmed.aam6310

Article Information

vol. 10 no. 430

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History: 
  • Received for publication December 19, 2016
  • Accepted for publication February 6, 2018
  • .

Author Information

  1. Mireille Kamariza1,*,
  2. Peyton Shieh2,*,
  3. Christopher S. Ealand3,
  4. Julian S. Peters3,
  5. Brian Chu2,
  6. Frances P. Rodriguez-Rivera2,
  7. Mohammed R. Babu Sait4,
  8. William V. Treuren5,
  9. Neil Martinson3,6,
  10. Rainer Kalscheuer4,
  11. Bavesh D. Kana3,7 and
  12. Carolyn R. Bertozzi2,8,
  1. 1Department of Biology, Stanford University, Stanford, CA 94305, USA.
  2. 2Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
  3. 3Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, Faculty of Health Sciences, University of Witwatersrand, National Health Laboratory Service, Johannesburg, South Africa.
  4. 4Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Duesseldorf, Universitätsstrasse 1, 40225 Duesseldorf, Germany.
  5. 5Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
  6. 6Perinatal HIV Research Unit (PHRU), SA MRC Soweto Matlosana Collaborating Centre for HIV/AIDS and TB, University of the Witwatersrand, Johannesburg, South Africa.
  7. 7Medical Research Council–Centre for the AIDS Programme of Research in South Africa (CAPRISA) HIV-TB Pathogenesis and Treatment Research Unit, Durban, South Africa.
  8. 8Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
  1. Corresponding author. Email: bertozzi{at}stanford.edu
    • * These authors contributed equally to this work.

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