Research ArticleCancer

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

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Science Translational Medicine  21 Feb 2018:
Vol. 10, Issue 429, eaan3682
DOI: 10.1126/scitranslmed.aan3682

Article Information

vol. 10 no. 429

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History: 
  • Received for publication April 3, 2017
  • Resubmitted July 18, 2017
  • Accepted for publication November 15, 2017
  • .

Author Information

  1. Chao Wang1,2,*,
  2. Jinqiang Wang1,2,*,
  3. Xudong Zhang1,2,
  4. Shuangjiang Yu1,2,
  5. Di Wen1,2,
  6. Quanyin Hu1,2,
  7. Yanqi Ye1,2,
  8. Hunter Bomba1,2,
  9. Xiuli Hu1,
  10. Zhuang Liu3,
  11. Gianpietro Dotti4 and
  12. Zhen Gu1,2,5,
  1. 1Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC 27695, USA.
  2. 2Division of Pharmacoengineering and Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  3. 3Institute of Functional Nano and Soft Materials, Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou 215123, China.
  4. 4Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  5. 5Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  1. Corresponding author. Email: zgu{at}email.unc.edu
    • * These authors contributed equally to this work.

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