Research ArticleDrug Discovery

High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds

See allHide authors and affiliations

Science Translational Medicine  21 Feb 2018:
Vol. 10, Issue 429, eaal3973
DOI: 10.1126/scitranslmed.aal3973

Article Information

vol. 10 no. 429

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 18, 2016
  • Resubmitted April 11, 2017
  • Accepted for publication September 27, 2017
  • .

Author Information

  1. Mattia Zampieri1,*,,
  2. Balazs Szappanos1,2,*,
  3. Maria Virginia Buchieri3,*,
  4. Andrej Trauner4,5,
  5. Ilaria Piazza6,
  6. Paola Picotti6,
  7. Sébastien Gagneux4,5,
  8. Sonia Borrell4,5,
  9. Brigitte Gicquel3,
  10. Joel Lelievre7,
  11. Balazs Papp2 and
  12. Uwe Sauer1
  1. 1Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
  2. 2Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary.
  3. 3Mycobacterial Genetics Unit, Institut Pasteur, 25-28 Rue du Docteur Roux, 75015 Paris, France.
  4. 4Swiss Tropical and Public Health Institute, Basel, Switzerland.
  5. 5University of Basel, Basel, Switzerland.
  6. 6Institute of Biochemistry, Department of Biology, ETH Zürich, Zürich, Switzerland.
  7. 7Disease of the Developing World, GlaxoSmithKline, Severo Ochoa, Tres Cantos, Madrid 28760, Spain.
  1. Corresponding author. Email: zampieri{at}imsb.biol.ethz.ch
    • * These authors contributed equally to this work.

    Altmetric

    Article usage

    Article usage: February 2018 to April 2021

    AbstractFullPdf
    Feb 20184800242573
    Mar 20181811169385
    Apr 20186767386
    May 20186214386
    Jun 20185385177
    Jul 20183245551
    Aug 201830510463
    Sep 20182468641
    Oct 201820610567
    Nov 201822510858
    Dec 20182167029
    Jan 20192237752
    Feb 20191709468
    Mar 201921315120
    Apr 20192724386
    May 201934247171
    Jun 201917194119
    Jul 20192017678
    Aug 201923175119
    Sep 201929168130
    Oct 20193015299
    Nov 201921167114
    Dec 20191715669
    Jan 20201911761
    Feb 20202311968
    Mar 202039137103
    Apr 202026110102
    May 20202213699
    Jun 20202013391
    Jul 2020418266
    Aug 2020348255
    Sep 20204510666
    Oct 20203615164
    Nov 20204010982
    Dec 20202711661
    Jan 20213113475
    Feb 20213613877
    Mar 20213915764
    Apr 20214211838

    Stay Connected to Science Translational Medicine

    Navigate This Article