Research ArticleEMERGING INFECTIONS
Zika virus–related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice
- View ORCID ProfileDerek J. Platt1,*,
- Amber M. Smith2,*,
- Nitin Arora3,4,
- Michael S. Diamond1,2,5,6,
- View ORCID ProfileCarolyn B. Coyne3,4 and
- View ORCID ProfileJonathan J. Miner1,2,5,†
- 1Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
- 2Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
- 3Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
- 4Center for Microbial Pathogenesis, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA.
- 5Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
- 6The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA.
- ↵†Corresponding author. Email: miner{at}wustl.edu
↵* These authors contributed equally to this work.
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Science Translational Medicine 31 Jan 2018:
Vol. 10, Issue 426, eaao7090
DOI: 10.1126/scitranslmed.aao7090
Vol. 10, Issue 426, eaao7090
DOI: 10.1126/scitranslmed.aao7090
Derek J. Platt
1Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Amber M. Smith
2Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Nitin Arora
3Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
4Center for Microbial Pathogenesis, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA.
Michael S. Diamond
1Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
2Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
5Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
6The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA.
Carolyn B. Coyne
3Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
4Center for Microbial Pathogenesis, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA.
Jonathan J. Miner
1Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
2Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
5Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.