Research ArticleCancer

Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett’s esophagus

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Science Translational Medicine  17 Jan 2018:
Vol. 10, Issue 424, eaao5848
DOI: 10.1126/scitranslmed.aao5848

Article Information

vol. 10 no. 424

PubMed: 
Print ISSN: 
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History: 
  • Received for publication August 7, 2017
  • Accepted for publication November 8, 2017
  • .

Author Information

  1. Helen R. Moinova1,
  2. Thomas LaFramboise2,3,
  3. James D. Lutterbaugh1,
  4. Apoorva Krishna Chandar1,
  5. John Dumot1,
  6. Ashley Faulx1,
  7. Wendy Brock1,
  8. Omar De la Cruz Cabrera4,
  9. Kishore Guda2,
  10. Jill S. Barnholtz-Sloan2,
  11. Prasad G. Iyer5,
  12. Marcia I. Canto6,
  13. Jean S. Wang7,
  14. Nicholas J. Shaheen8,
  15. Prashanti N. Thota9,
  16. Joseph E. Willis2,10,11,*,,
  17. Amitabh Chak1,2,11,*, and
  18. Sanford D. Markowitz1,2,3,11,*,
  1. 1Department of Medicine, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
  2. 2Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA.
  3. 3Department of Genetics and Genome Sciences, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
  4. 4Department of Mathematical Sciences, Kent State University, Kent, OH 44242, USA.
  5. 5Barrett’s Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA.
  6. 6Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA.
  7. 7Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  8. 8Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  9. 9Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
  10. 10Department of Pathology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
  11. 11University Hospitals Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
  1. *Corresponding author. Email: sxm10{at}cwru.edu (S.D.M.); josephe.willis{at}uhhospitals.org (J.E.W.); amitabh.chak{at}uhhospitals.org (A.C.)
    • These authors contributed equally to this work.

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