Research ArticleNanomedicine
Inhalation of peptide-loaded nanoparticles improves heart failure
- Michele Miragoli1,2,3,*,†,
- Paola Ceriotti1,3,*,
- Michele Iafisco4,
- Marco Vacchiano1,
- Nicolò Salvarani1,3,
- Alessio Alogna5,6,
- Pierluigi Carullo1,3,
- Gloria Belén Ramirez-Rodríguez4,
- Tatiana Patrício4,
- Lorenzo Degli Esposti4,
- Francesca Rossi7,
- Francesca Ravanetti8,
- Silvana Pinelli2,
- Rossella Alinovi2,
- Marco Erreni1,9,
- Stefano Rossi2,
- Gianluigi Condorelli1,3,9,
- Heiner Post5,10,
- Anna Tampieri4 and
- Daniele Catalucci1,3,†
- 1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
- 2Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
- 3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
- 4Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
- 5Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité University Medicine Berlin, Berlin 13353, Germany.
- 6Berlin Institute of Health, Berlin 10117, Germany.
- 7Institute of Materials for Electronics and Magnetism, National Research Council, Parma 43126, Italy.
- 8Department of Veterinary Science, University of Parma, Parma 43126, Italy.
- 9Humanitas University, Rozzano, Milan 20089, Italy.
- 10Department of Cardiology, Contilia Heart and Vessel Centre, St. Marien-Hospital Mülheim, Mülheim 45468, Germany.
- ↵†Corresponding author. Email: michele.miragoli{at}humanitasresearch.it (M.M.); daniele.catalucci{at}cnr.it (D.C.)
↵* These authors contributed equally to this work.
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Science Translational Medicine 17 Jan 2018:
Vol. 10, Issue 424, eaan6205
DOI: 10.1126/scitranslmed.aan6205
Vol. 10, Issue 424, eaan6205
DOI: 10.1126/scitranslmed.aan6205
Michele Miragoli
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Paola Ceriotti
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Michele Iafisco
Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Marco Vacchiano
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
Nicolò Salvarani
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Alessio Alogna
Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité University Medicine Berlin, Berlin 13353, Germany.Berlin Institute of Health, Berlin 10117, Germany.
Pierluigi Carullo
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Gloria Belén Ramirez-Rodríguez
Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Tatiana Patrício
Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Lorenzo Degli Esposti
Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Francesca Rossi
Institute of Materials for Electronics and Magnetism, National Research Council, Parma 43126, Italy.
Francesca Ravanetti
Department of Veterinary Science, University of Parma, Parma 43126, Italy.
Silvana Pinelli
Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
Rossella Alinovi
Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
Marco Erreni
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.Humanitas University, Rozzano, Milan 20089, Italy.
Stefano Rossi
Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
Gianluigi Condorelli
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.Humanitas University, Rozzano, Milan 20089, Italy.
Heiner Post
Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité University Medicine Berlin, Berlin 13353, Germany.Department of Cardiology, Contilia Heart and Vessel Centre, St. Marien-Hospital Mülheim, Mülheim 45468, Germany.
Anna Tampieri
Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Daniele Catalucci
Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
