Research ArticleNanomedicine
Inhalation of peptide-loaded nanoparticles improves heart failure
- View ORCID ProfileMichele Miragoli1,2,3,*,†,
- View ORCID ProfilePaola Ceriotti1,3,*,
- View ORCID ProfileMichele Iafisco4,
- View ORCID ProfileMarco Vacchiano1,
- View ORCID ProfileNicolò Salvarani1,3,
- Alessio Alogna5,6,
- View ORCID ProfilePierluigi Carullo1,3,
- View ORCID ProfileGloria Belén Ramirez-Rodríguez4,
- View ORCID ProfileTatiana Patrício4,
- View ORCID ProfileLorenzo Degli Esposti4,
- View ORCID ProfileFrancesca Rossi7,
- View ORCID ProfileFrancesca Ravanetti8,
- View ORCID ProfileSilvana Pinelli2,
- View ORCID ProfileRossella Alinovi2,
- View ORCID ProfileMarco Erreni1,9,
- View ORCID ProfileStefano Rossi2,
- View ORCID ProfileGianluigi Condorelli1,3,9,
- Heiner Post5,10,
- View ORCID ProfileAnna Tampieri4 and
- View ORCID ProfileDaniele Catalucci1,3,†
- 1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
- 2Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
- 3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
- 4Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
- 5Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité University Medicine Berlin, Berlin 13353, Germany.
- 6Berlin Institute of Health, Berlin 10117, Germany.
- 7Institute of Materials for Electronics and Magnetism, National Research Council, Parma 43126, Italy.
- 8Department of Veterinary Science, University of Parma, Parma 43126, Italy.
- 9Humanitas University, Rozzano, Milan 20089, Italy.
- 10Department of Cardiology, Contilia Heart and Vessel Centre, St. Marien-Hospital Mülheim, Mülheim 45468, Germany.
- ↵†Corresponding author. Email: michele.miragoli{at}humanitasresearch.it (M.M.); daniele.catalucci{at}cnr.it (D.C.)
↵* These authors contributed equally to this work.
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Science Translational Medicine 17 Jan 2018:
Vol. 10, Issue 424, eaan6205
DOI: 10.1126/scitranslmed.aan6205
Vol. 10, Issue 424, eaan6205
DOI: 10.1126/scitranslmed.aan6205
Michele Miragoli
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
2Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Paola Ceriotti
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Michele Iafisco
4Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Marco Vacchiano
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
Nicolò Salvarani
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Alessio Alogna
5Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité University Medicine Berlin, Berlin 13353, Germany.
6Berlin Institute of Health, Berlin 10117, Germany.
Pierluigi Carullo
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
Gloria Belén Ramirez-Rodríguez
4Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Tatiana Patrício
4Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Lorenzo Degli Esposti
4Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Francesca Rossi
7Institute of Materials for Electronics and Magnetism, National Research Council, Parma 43126, Italy.
Francesca Ravanetti
8Department of Veterinary Science, University of Parma, Parma 43126, Italy.
Silvana Pinelli
2Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
Rossella Alinovi
2Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
Marco Erreni
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
9Humanitas University, Rozzano, Milan 20089, Italy.
Stefano Rossi
2Department of Medicine and Surgery, University of Parma, Parma 43126, Italy.
Gianluigi Condorelli
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
9Humanitas University, Rozzano, Milan 20089, Italy.
Heiner Post
5Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité University Medicine Berlin, Berlin 13353, Germany.
10Department of Cardiology, Contilia Heart and Vessel Centre, St. Marien-Hospital Mülheim, Mülheim 45468, Germany.
Anna Tampieri
4Institute of Science and Technology for Ceramics, National Research Council, Faenza, Ravenna 48018, Italy.
Daniele Catalucci
1Humanitas Clinical and Research Center, Rozzano, Milan 20089, Italy.
3Institute of Genetics and Biomedical Research, Milan Unit, National Research Council, Milan 20138, Italy.
