Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction

Dennis Jones; Eelco F. J. Meijer; Cedric Blatter; Shan Liao; Ethel R. Pereira; Echoe M. Bouta; Keehoon Jung; Shan Min Chin; Peigen Huang; Lance L. Munn; Benjamin J. Vakoc; Michael Otto; Timothy P. Padera

doi:10.1126/scitranslmed.aam7964

Research ArticleVascular Biology

Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction

Dennis Jones¹,²,
Eelco F. J. Meijer¹,²,
Cedric Blatter²,³,
Shan Liao¹,*,
Ethel R. Pereira¹,²,
Echoe M. Bouta¹,²,
Keehoon Jung¹,²,
Shan Min Chin¹,²,
Peigen Huang¹,²,
Lance L. Munn¹,²,
Benjamin J. Vakoc²,³,
Michael Otto⁴ and
Timothy P. Padera¹,²,†

¹Edwin L. Steele Laboratory, Department of Radiation Oncology, MGH Cancer Center, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA.
²Harvard Medical School, Boston, MA 02115, USA.
³Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.
⁴Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.

↵†Corresponding author. Email: tpadera{at}steele.mgh.harvard.edu

↵* Present address: Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, 3330 Hospital Drive Northwest, Calgary, Alberta T2N 4N1, Canada.

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Science Translational Medicine 17 Jan 2018:
Vol. 10, Issue 424, eaam7964
DOI: 10.1126/scitranslmed.aam7964

Dennis Jones

Edwin L. Steele Laboratory, Department of Radiation Oncology, MGH Cancer Center, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA.Harvard Medical School, Boston, MA 02115, USA.

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Eelco F. J. Meijer

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Cedric Blatter

Harvard Medical School, Boston, MA 02115, USA.Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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Shan Liao

Edwin L. Steele Laboratory, Department of Radiation Oncology, MGH Cancer Center, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA.

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Ethel R. Pereira

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Echoe M. Bouta

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Keehoon Jung

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Shan Min Chin

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Peigen Huang

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Lance L. Munn

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Benjamin J. Vakoc

Harvard Medical School, Boston, MA 02115, USA.Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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Michael Otto

Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.

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Timothy P. Padera

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For correspondence: tpadera@steele.mgh.harvard.edu

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Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction

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