Editors' ChoiceCancer

Novel drug combination unleashes apoptosis in AML

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Science Translational Medicine  03 Jan 2018:
Vol. 10, Issue 422, eaar7509
DOI: 10.1126/scitranslmed.aar7509


The combination of p53 activation and Bcl-2 inhibition reciprocally overcomes apoptosis resistance and leads to synergistic efficacy in acute myeloid leukemia.

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