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Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials

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Science Translational Medicine  03 Jan 2018:
Vol. 10, Issue 422, eaao0475
DOI: 10.1126/scitranslmed.aao0475

Article Information

vol. 10 no. 422

DOI: 
https://doi.org/10.1126/scitranslmed.aao0475
PubMed: 
29298864
Published By: 
American Association for the Advancement of Science
Print ISSN: 
1946-6234
Online ISSN: 
1946-6242
History: 
  • Received for publication June 12, 2017
  • Accepted for publication December 8, 2017
  • .
Copyright & Usage: 
Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License.

Author Information

  1. Marsha C. Lampi1 and
  2. Cynthia A. Reinhart-King2,*
  1. 1Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14850, USA.
  2. 2Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37212, USA.
  1. ↵*Corresponding author. Email: cynthia.reinhart-king{at}vanderbilt.edu

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  • Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials

    By Marsha C. Lampi, Cynthia A. Reinhart-King

    Science Translational Medicine

    Targeting extracellular matrix stiffness holds clinical potential to attenuate pathological progression in the emerging field of mechanomedicine.

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