PerspectiveMénétrier’s Disease

Ménétrier’s Disease Therapy: Rebooting Mucosal Signaling

See allHide authors and affiliations

Science Translational Medicine  25 Nov 2009:
Vol. 1, Issue 8, pp. 8ps10
DOI: 10.1126/scitranslmed.3000438

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


Ménétrier’s disease, a rare hyperproliferative disorder of the stomach, is associated with chronic abdominal pain, vomiting, weight loss, and edema, as well as an increased risk of gastric cancer. Therapy, other than surgical resection of the stomach, is limited to supportive measures and reflects the limited understanding of Ménétrier’s disease pathogenesis. Data reported in this issue describe a promising targeted therapeutic approach and provide new insight into the causes of Ménétrier’s disease.


  • Citation: S. C. Nalle, J. R. Turner, Ménétrier’s disease therapy: Rebooting mucosal signaling. Sci. Transl. Med. 1, 8ps10 (2009).

View Full Text

Stay Connected to Science Translational Medicine