Contents
Vol 1, Issue 3
Contents
Commentary
- What the Patient Should Order
Clinical information must be converted into research data that can be aggregated to provide a sufficiently large set for reliable analyses to inform health care decisions.
Perspective
- Computational Genetic Mapping in Mice: The Ship Has Sailed
Computational haplotype-based genetic mapping can be used to discover new biological mechanisms and unexpected uses for existing drugs.
Research Articles
- Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling
Inhibition of a membrane receptor protects normal tissue from radiation injury and simultaneously enhances the ability of ionizing radiation to delay tumor growth.
- Slow Elimination of Multidrug-Resistant Tuberculosis
The spread of drug-resistant tuberculosis may be halted and reversed through appropriate use of drugs and diagnostics.
Editors' Choice
- My Heart's All Aflutter
Specialized cells in the heart similar to skin melanocytes may trigger the common heart arrhythmia, atrial fibrillation.
- Fishermen and Farmers Share SNPs and Severe Fibrosis
Single-nucleotide polymorphisms found in ethnically and geographically diverse populations correlate with schistosomiasis-associated severe liver fibrosis.
- Pleasure or Pain: A Matter of Perception
Scientists use imaging technology to pinpoint a specific region of the central nervous system involved in pain relief caused by placebos in humans.
- Rebuilding Broken Bones
Geometrically complex bone structures can be engineered with human stem cells and a customized bone scaffold.
