23 December 2009
Vol 1, Issue 12

About The Cover

Cover image expansion

ONLINE COVER A domestic ferret, Mustela putorius furo. Ferrets make good experimental subjects for studying influenza viruses because they catch flu just as humans do, exhibiting similar respiratory symptoms. Flu viruses attach to ferret tracheal cells and to cells deeper in the respiratory tract in the same way that they bind to human lung cells. In this issue, Del Guidice et al. report experiments in ferrets showing that receiving the seasonal flu vaccine increases the effectiveness of a subsequent immunization to AH1N1 influenza. [CREDIT: JUPITERIMAGES]