Contents
Vol 1, Issue 11
Contents
Perspectives
- Pharmacologic Induction of CD8+ T Cell Memory: Better Living Through Chemistry
Drugs already in clinical use can enhance the generation of memory T cells, creating new prospects for T cell–based immunotherapies for infectious diseases and cancer.
- Toward a Systems-Level Analysis of Infection Biology: A New Method for Conducting Genetic Screens in Human Cells
A library of loss-of-function alleles generated from a largely haploid human cell line facilitated genome-wide screens designed to interrogate host-pathogen interactions and promote a systems-level understanding of infectious disease.
Research Article
- Intravenous Hemostat: Nanotechnology to Halt Bleeding
Synthetic platelets composed of functionalized nanoparticles halve bleeding time in a rat injury model and may prove useful in treating human trauma victims.
Editors' Choice
- Protection from Hemoglobin's Dark Side
A naturally occurring protein that binds hemoglobin protects the brain from damage after a bleeding stroke, offering a potential therapeutic approach.
- Metabolites on the Brain
A mutated metabolic enzyme gains a new catalytic activity that may enhance the progression of metastatic brain cancer.
- Where to PARK?
A gene mutated in familial Parkinson's disease is now linked to brain cancer.
