Table 4 Relationship of NREM SWA to Aβ42 after adjusting for age, sex, race, CDR, ApoE4 status, AHI, PLMI, sleep medications, and time.

Linear mixed models were used to calculate the estimates and P values for the 104 participants with CSF.

Dependent variableCovariateEstimateSEF statistic
(df)
P
1–4.5 Hz SWAAβ42+0.0040.0031.44 (1,10)0.257
Age+0.0210.1880.01 (1,12)0.911
Sex+0.4572.6870.03 (1,12)0.868
CDR+8.2703.3046.27 (1,15)0.024
Race−10.0313.9106.58 (1,10)0.029
ApoE4 status−6.5972.8975.18 (1,11)0.044
Sleep medications−17.9106.1028.62 (1,12)0.013
AHI−0.0070.1510.00 (1,11)0.966
PLMI+0.0550.0411.83 (1,13)0.199
Time−0.1740.1671.08 (1,76)0.302
1–2 Hz SWAAβ42+0.0080.0071.48 (1,11)0.248
Age+0.0770.4470.03 (1,12)0.866
Sex+0.9006.3940.02 (1,12)0.890
CDR+18.0827.8735.28 (1,16)0.036
Race−21.7159.3015.45 (1,11)0.040
ApoE4 status−15.5656.8945.10 (1,12)0.044
Sleep medications−44.69514.5249.47 (1,13)0.009
AHI−0.0560.3600.02 (1,12)0.879
PLMI+0.0860.0970.78 (1,14)0.393
Time−0.4890.4011.49 (1,77)0.226
2–3 Hz SWAAβ42+0.0030.0022.44 (1,9)0.153
Age+0.0030.1280.00 (1,11)0.980
Sex+0.2991.8460.03 (1,11)0.874
CDR+7.2272.20310.76 (1,14)0.005
Race−8.6542.7399.98 (1,8)0.013
ApoE4 status−5.3722.0097.15 (1,10)0.024
Sleep medications−13.9414.19811.03 (1,11)0.007
AHI+0.0160.1050.02 (1,10)0.884
PLMI+0.0590.0284.52 (1,12)0.054
Time−0.0850.1250.47 (1,16)0.504
3–4 Hz SWAAβ42+0.0020.0014.09 (1,12)0.066
Age−0.0230.0720.10 (1,13)0.759
Sex−0.2161.0270.04 (1,13)0.837
CDR+2.6231.0745.97 (1,12)0.032
Race−3.3011.5384.61 (1,12)0.053
ApoE4 status−1.9641.1213.07 (1,13)0.104
Sleep medications−6.3872.2677.94 (1,12)0.016
AHI+0.0180.0580.10 (1,12)0.763
PLMI+0.0240.0152.72 (1,13)0.124
Time−0.0120.0520.06 (1,15)0.815