Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. RT and non-RT tonsillar immunophenotyping of cohort 1.
  • Fig. S2. RT and non-RT tonsillar immunophenotyping of cohort 2.
  • Fig. S3. GAS-specific CD4+ T cells by AIM assay.
  • Fig. S4. HLA typing of entire tonsillar cohort.
  • Fig. S5. SpeA-responsive GC-TFH cells.
  • Fig. S6. SpeA-responsive GC-TFH cells by AIM assay.
  • Fig. S7. SpeA induced GzmB production.
  • Fig. S8. SpeA-responsive GC-TFH cells by AIM assay.
  • Table S1. RNA-seq analysis.
  • Table S2. Flow cytometry antibodies for fresh tonsil stain.
  • Table S3. Flow cytometry antibodies for AIM assay.
  • Table S4. Flow cytometry antibodies for PBMC proliferation assay.
  • Table S5. Flow cytometry antibodies for GzmB detection.
  • Table S6. Flow cytometry antibodies used for sorting GC-TFH and non-BGC cells for GzmB expression after 5-day in vitro culture.
  • Table S7. Flow cytometry antibodies for GzmB detection from sorted GC-TFH cells.
  • Table S8. Flow cytometry antibodies used for sorting for cytotoxicity assay.
  • References (5970)

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Other Supplementary Material for this manuscript includes the following: